Warwickshire police is appealing for witnesses.
It happened on Saturday afternoon at around 1.50pm.
In a statement, the force said: "a single vehicle collision took place on Kingswood Road, involving a grey Yamaha MT125cc motorcycle.
The motorcyclist, a man in his mid-20s, was taken to hospital where he sadly died on Sunday.
Road closures were in place whilst emergency services were in attendance."
M1 closed northbound due to 'serious collison'
Police say to find alternative routes.
Emergency sewer pipe repairs on A5 in Hinckley
Temporary traffic lights are by the BP garage.
The UK's only bonobo baby born at Twycross Zoo
"The birth of this baby bonobo is a truly extraordinary moment, not just for Twycross Zoo, but globally."
Appeal after sexual touching on bus
Officers would like to identify a man.
Exhibition remembering the end of the Second World War is now open in Hinckley
The exhibition is open until Friday 26 September.
Hinckley New Look will close this year
The shop is in the heart of Hinckley town centre.
School creates book of remembrance to honour English teacher who had 'impact on so many'
The book will be a place to 'celebrate his teaching life.'
University Hospitals of Leicester NHS Trust part of national investigation
They have said they welcome the investigation and will work openly with the investigation team.
Medium-level cloud
16°C
Sunny intervals
17°C
Low-level cloud
16°C
Sunny intervals
18°C
Midnight - 6:00am
Up late or up early, we've got Just Great Music interruption-free.
6:00am - 8:00am
Non stop music on your Saturday morning
Voyage Voyage
Desireless
Your Song
Elton John
Girls Like You
Maroon 5
Even Better Than The Real Thing
U2